CD40 Polyclonal Antibody
SKU: E-AB-16318-200
CD40 Polyclonal Antibody
| SKU # | E-AB-16318 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human CD40 |
| Abbre | CD40 |
| Synonyms | AI326936, B cell associated molecule CD40, B cell surface antigen CD40, B cell-associated molecule, B-cell surface antigen CD40, Bp50, CD 40, CD40, CD40 antigen, CD40 antigen (TNF receptor superfamily member 5), CD40 molecule, TNF receptor superfamily |
| Swissprot | |
| Cellular Localization | Secreted and Cell membrane. |
| Concentration | 1.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Immunology, Stem cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:100-1:300 |
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily.This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, whicHuman, Mouseay be important for homotypic cell interactions.Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction.The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.