CD146 Monoclonal Antibody Synonyms CD146
SKU: PA7194-1.5
CD146 Monoclonal Antibody Synonyms CD146
Product Details
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC-P |
| Synonyms | CD146 |
| Cellular Localization | cell membrane/Cytoplasm |
| Tissue Specificity | melanoma |
| Storage | The RTU should be stored at 2~8°C protecting from light (Do not freeze),Valid for 12 months. |
| Shipping | Ice bag |
Background
CD146, also known as melanoma cell adhesion molecule (MCAM) with a molecular weight of 113kDa, is expressed on various human endothelial cells and is involved in tumor angiogenesis and metastasis. It is initially found in malignant melanoma, whereas normal melanocytes do not express it. In addition, CD146 is also widely present in a variety of tissues and tumors. If expressed on intermediate trophoblastic cells, it can be used in combination with other antibodies for the identification of trophoblastic tumors.