CASQ1 Polyclonal Antibody
SKU: E-AB-52513-200
CASQ1 Polyclonal Antibody
| SKU # | E-AB-52513 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human CASQ1 |
| Abbre | CASQ1 |
| Synonyms | cell, skeletal muscle isoform, skeletal muscle), CASQ, CASQ1, Calmitin, Calmitine, Calsequestrin, Calsequestrin 1 (fast twitch, Calsequestrin-1, Casq1, PDIB1, skeletal muscle isoform |
| Swissprot | |
| Cellular Localization | Sarcoplasmic reticulum lumen. Mitochondrion. This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of fast skeletal muscle cells. Also mitochondrial according to PubMed:7945294. |
| Concentration | 1.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
Background
This gene encodes the skeletal muscle specific member of the calsequestrin protein family.Calsequestrin functions as a luminal sarcoplasmic reticulum calcium sensor in both cardiac and skeletal muscle cells.This protein, also known as calmitine, functions as a calcium regulator in the mitochondria of skeletal muscle.This protein is absent in patients with Duchenne and Becker types of muscular dystrophy.