Carboxypeptidase B2 Polyclonal Antibody
SKU: E-AB-40640-100
Carboxypeptidase B2 Polyclonal Antibody
| SKU # | E-AB-40640 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant Human CPB2 protein expressed by E.coli. |
| Abbre | CPB2 |
| Synonyms | CPB2, CPU, Carboxypeptidase B2, Carboxypeptidase U, Plasma carboxypeptidase B, TAFI, Thrombin-activable fibrinolysis inhibitor, pCPB |
| Swissprot | |
| Calculated MW | 48 kDa |
| Observed MW | 56 kDa |
| Cellular Localization | Secreted |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cardiovascular, Signal Transduction, Metabolism |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:250-1:500 |
Background
CPB2 (Carboxypeptidase B2; also CPU and TAFI) is a secreted,50-60 kDa glycoprotein member of the peptidase M14 family of enzymes. It is expressed by hepatocytes (60 kDa) and platelets (50 kDa),with MW differences attributable to glycosylation. CPB2 is cleaved by thrombin and plasmin, generating a 36 kDa,relatively insoluble nonglycosylated enzymatically active fragment (TAFIa).