CAMK2A Polyclonal Antibody
SKU: E-AB-19660-200
CAMK2A Polyclonal Antibody
| SKU # | E-AB-19660 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human CAMK2A |
| Abbre | CAMK2A |
| Synonyms | Alpha CaMKII, Ca, Calcium calmodulin dependent protein kinase II, Calcium/calmodulin dependent protein kinase II alpha B subunit, Calcium/calmodulin dependent protein kinase type II alpha chain, Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha |
| Swissprot | |
| Cellular Localization | Cell junction>synapse>presynaptic cell membrane. Cell junction>synapse. Postsynaptic lipid rafts. |
| Concentration | 0.8 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:40-1:200 |
Background
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily.Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses.This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta.The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning.In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity.Two transcript variants encoding distinct isoforms have been identified for this gene.