C12orf5 Polyclonal Antibody Store at -20°C
SKU: E-AB-16101-200
C12orf5 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-16101 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human C12orf5 |
| Abbre | C12orf5 |
| Synonyms | 6 bisphosphatase TIGAR, 6-bisphosphatase TIGAR, 6-bisphosphate 2-phosphatase, C12ORF5, FR2BP, Fructose-2, Probable fructose 2, Probable fructose-2, TIGAR, TP53 induced glycolysis and apopto, chromosome 12 open reading frame 5, tigar |
| Swissprot | |
| Cellular Localization | Cytosol, Mitochondrion, mitochondrial outer membrane, Nucleus, Other locations: cytoplasm, intracellular. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:100-1:300 |
Background
This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region.