Beta Tubulin Monoclonal Antibody
SKU: E-AB-20093-200
Beta Tubulin Monoclonal Antibody
| SKU # | E-AB-20093 |
| Reactivity | Human, Mouse, Rat |
| Host | Mouse |
| Applications | WB, IF |
Product Details
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IF |
| Clonality | Monoclonal |
| Immunogen | Synthetic Peptide |
| Abbre | β-tubulin |
| Synonyms | CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, M(beta)3, M(beta)6, MC1R, Neuron specific beta III Tubulin, Neuron-specific class III beta-tubulin, QccE-11995, QccE-15186, TBB3, TUBB3, TUBB4, Tubb 3, Tubulin, Tubulin beta 3, Tubulin beta 3 chain, Tubulin beta 4, beta 3 tubulin, beta-4 |
| Swissprot | |
| Calculated MW | 50 kDa |
| Observed MW | 55 kDa |
| Cellular Localization | Cytoplasm>cytoskeleton. |
| Tissue Specificity | Expression is primarily restricted to central and peripheral nervous system. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Research Areas | Cancer, Neuroscience, Signal Transduction, Tags and Cell Markers |
| Clone No. | 4A6 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:5000-10000 |
| IF | 1:100-200 |
Background
TUBB3,the class III β tubulin or Tuj1,is selectively expressed in testis and neurons of the central and peripheral nervous system. It has been widely used as a marker for neurons. Aberrant expression of TUBB3 has also been found in various tumors of non-neural origin and can be used as a biomarker for cancer aggressiveness and a marker for the tendency to respond poorly to chemotherapy. This antibody is specific to TUBB3 but not cross-react with other tubulin isoforms.