Anti-SARS-CoV Spike S1 Monoclonal Antibody
SKU: E-AB-V1350-100
Anti-SARS-CoV Spike S1 Monoclonal Antibody
| SKU # | E-AB-V1350 |
| Reactivity | SARS |
| Host | Mouse |
| Applications | WB, ELISA |
Product Details
| Isotype | IgG2a |
| Host | Mouse |
| Reactivity | SARS |
| Applications | WB, ELISA |
| Clonality | Monoclonal |
| Immunogen | Recombinant SARS-CoV S1 Protein (His Tag)（Active） |
| Synonyms | RBD, S1, Spike RBD, coronavirus s1, coronavirus spike, cov spike, ncov RBD, ncov s1, ncov spike, novel coronavirus RBD, novel coronavirus s1, novel coronavirus spike |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS. |
| Purification Method | Protein A Affinity |
| Clone No. | 08 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:5000 |
| ELISA | 1:1000-1:2000 |
Background
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of heterologous proteins on the virus surface that function together. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process.