Amphiphysin I Polyclonal Antibody Store at -20°C
SKU: E-AB-13895-200
Amphiphysin I Polyclonal Antibody Store at -20°C
| SKU # | E-AB-13895 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human AMPH |
| Abbre | Amphiphysin I |
| Synonyms | AMPH, AMPH 1, AMPH1, Amp, Amphiphysin, Amphiphysin (Stiff-Man syndrome with breast cancer 128kD autoantigen), Amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen), Amphiphysin I, CG8604, Damp, Dmel\CG8604, HGNC:471, MGC49429, Stiff man syn, dAmph |
| Swissprot | |
| Calculated MW | 76 kDa |
| Cellular Localization | Cytoplasmic vesicle>secretory vesicle>synaptic vesicle membrane. Cytoplasm>cytoskeleton. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Immunology, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.