ALDH3A1 Polyclonal Antibody Store at -20°C
SKU: E-AB-14534-200
ALDH3A1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14534 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human ALDH3A1 |
| Abbre | ALDH3A1 |
| Synonyms | AHD 4, AHD C, AHD4, AHDC, AL3A1, Acetaldehyde dehydrogenase 3, Ald, Aldehyde dehydrogenase, Aldehyde dehydrogenase 3, Aldehyde dehydrogenase 3 family member A1, Aldehyde dehydrogenase 3A1, Aldehyde dehydrogenase class 3, Aldehyde dehydrogenase dimeric NADP preferring |
| Swissprot | |
| Calculated MW | 50 kDa |
| Cellular Localization | Cytoplasm. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Metabolism, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified.