ACTC1 Polyclonal Antibody Reactivity Human
SKU: E-AB-52617-200
ACTC1 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52617 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human ACTC1 |
| Abbre | ACTC1 |
| Synonyms | ACTC, ACTC1, ASD5, Actin, Actin alpha cardiac muscle 1, Alpha-cardiac actin, CMD1R, CMH11, LVNC4, alpha cardiac muscle 1 |
| Swissprot | |
| Cellular Localization | Cytoplasm>cytoskeleton. |
| Concentration | 1.14 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cardiovascular, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
Actins are highly conserved proteins that are involved in various types of cell motility.Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix.Each actin can bind to four others.The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma.The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus.Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).