ABI3BP Polyclonal Antibody Store at -20°C
SKU: E-AB-14758-200
ABI3BP Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14758 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human ABI3BP |
| Abbre | ABI3BP |
| Synonyms | ABI gene family member 3 (NESH) binding protein, ABI gene family member 3 binding protein, ABI gene family member 3-binding protein, ABI3BP, FLJ41743, FLJ41754, Nesh BP, Nesh binding protein, Nesh-binding protein, NeshBP, Target of Nesh SH3, Target of Nesh-SH3, Tarsh |
| Swissprot | |
| Cellular Localization | Secreted. |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
A target of NESH-SH3/Abi3bp (TARSH) was originally identified as an SH3 domain-binding molecule of the NESH-SH3/Abi3 protein that is involved in Rac-dependent actin polymerization. In recent studies, TARSH gene expression was dramatically induced in mouse embryonic fibroblasts (MEFs) replicative senescence and suppressed in human lung carcinoma specimens and thyroid carcinomas. However, the molecular mechanism underlying the regulation of TARSH in tumorigenesis remains unclear.