Tribioscience Tunicamycin, ER Stress Inducer (TBI2111)
Couldn't load pickup availability
Still have questions? Ask our experts!
Tribioscience Tunicamycin, ER Stress Inducer (TBI2111)
Buy Tribioscience products from MSE Supplies at the best value.
Product Details
Molecular Formula: C38H62N4O16 (tun. B)
Formula Weight: 830.9
CAS Number: 11089-65-9
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
Storage: -20°C
Stability: ≥ 2 years.
Applications
ER stress inducer
Functions
Fermentation product from Streptomyces lysosuperificus. Provided as a mixture of tunicamycin A (C14), B (C15), C (C16) and D (C17) homologs varying in the number of carbon atoms in the fatty acid chain.
Potent inhibitor of GlcNAc phosphotransferase which thereby inhibits glycoprotein biosynthesis. Causes endoplasmic reticulum stress-induced autophagy and unfolded protein response. Arrests cell cycle in late G1.
Application Procedures
First dissolved in DMSO (up to 40 mg/ml) or in Ethanol (up to 5 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.