Tribioscience LPA (Oleyl), Endogenous LPA Receptor Agonist (TBI1449)
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Tribioscience LPA (Oleyl), Endogenous LPA Receptor Agonist (TBI1449)
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Product Details
Formal Name: 1-Oleoyl-2-hydroxy-sn-glycerol-3-phosphate, sodium
Alternate Names: LPA · Na; 1-Oleoyl-lysophosphatidic acid, sodium salt
Molecular Formula: C21H40O7P
Formula Weight: 458.51
CAS Number: 325465-93-8
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 1 mg/ml with warming) or in Water (up to 10 mg/ml with warming).
Storage: -20°C
Stability: ≥ 2 years.
Applications
Endogenous LPA receptor agonist
Functions
A multifunctional intercellular bioactive phospholipid. Stimulates the growth of a variety of cells including fibroblasts, vascular smooth muscle cells, endothelial cells and keratinocytes among others1. Acts as a proliferative and anti-apoptotic factor. Agonist at LPA1 (EDG-2), LPA2 (EDG-4) and LPA3 (EDG-7) receptors. LPA-primed astrocytes induce axonal outgrowth of cortical progenitors.
Application Procedures
First dissolved in DMSO (up to 1 mg/ml with warming) or in Water (up to 10 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.