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Description: CD40 is a cell surface receptor that belongs to the tumor necrosis factor receptor (TNFR) superfamily and was initially identified on B lymphocytes. It plays a crucial role in T cell-dependent humoral immune responses and is involved in the activation, growth, differentiation, and survival of B cells. CD40 is expressed on a variety of cell types, including monocytes, dendritic cells, endothelial cells, epithelial cells, macrophages, fibroblasts, and platelets.
Applications:
- in vivo CD40 activation
- in vitro B cell stimulation/activation
Molecular Weight: 150 kDa
Host: Rat
Isotype: Rat IgG2a
Concentration: 4 mg/ml
Purity: >95%
Formulation: PBS, pH 7.0, no stabilizers or preservatives.
Endotoxin: < 2EU/mg
Clonality: Monoclonal
Sterility: 0.2 µm filtered
Storage: Store at 4°C for one month. Store at -20°C for long-term storage.