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Description: CD137, also known as 4-1BB, is a member of the tumor necrosis factor receptor (TNFR) superfamily. It is expressed on activated T cells, natural killer (NK) cells, dendritic cells, and other immune cells. CD137 plays a crucial role in the activation and survival of T cells and NK cells. It provides a co-stimulatory signal that enhances the proliferation, cytokine production, and cytotoxic activity of these cells.
Applications:
- in vivo 4-1BB stimulation
- in vitro 4-1BB stimulation
Molecular Weight: 150 kDa
Host: Rat
Isotype: Rat IgG2a
Concentration: 4 mg/ml
Purity: >95%
Formulation: PBS, pH 7.0, no stabilizers or preservatives.
Endotoxin: < 2EU/mg
Clonality: Monoclonal
Sterility: 0.2 µm filtered
Storage: Store at 4°C for one month. Store at -20°C for long-term storage.