Product Detail
Formal Name: 1-Benzoyl-3-phenyl-2-thiourea
Molecular Formula: C14H12N2OS
Formula Weight: 256.32
CAS Number: 4921-82-8
Purity: >98%
Formulation: Powder
Solubility: Soluble in DMSO (greater than 50 mg/ml) or in Ethanol (up to 8 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
HDAC8 activator
Functions
Highly potent and isozyme selective activator of recombinant HDAC8. Increases the activity of HDAC8 by a factor of 12 at 10 μM. No activation of other HDACs is observed. Rescues the activity of catalytically compromised HDAC8 mutants in vitro.
Application Procedures
First dissolved in DMSO (greater than 50 mg/ml) or in Ethanol (up to 8 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.