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Tribioscience Minoxidil, K-ATP Channel Opener (TBI1214)

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SKU: TBI1214-100MG
Regular price $ 87.95

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Tribioscience Minoxidil, K-ATP Channel Opener (TBI1214)

Research Use Only. Not intended for human use.

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Product Details

Formal Name: 6-Piperidine-1-ylpyrimidine-2,4-diamine 3-oxide

Molecular Formula: C9H15N5O

Formula Weight: 209.25

CAS Number: 38304-91-5

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 5 mg/ml).

Storage: RT

Stability: ≥ 2 years.

Applications

K-ATP channel opener

Functions

Minoxidil is a direct antihypertensive peripheral vasodilator acting via activation of KATP channels leading to relaxation of smooth muscle. Active metabolite is Minoxidil sulfate (IC50 = 0.14 µM).  Mainly used as a treatment for alopecia because of its observed hair regrowth ability.

Application Procedures

First dissolved in DMSO (up to 5 mg/ml) or in Ethanol (up to 5 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or Ethanol may be stored at -20°C for up to 3 months.

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