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Tribioscience Herbimycin A, HSP90 Inhibitor; Src Inhibitor (TBI2567)

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SKU: TBI2567-100UG
Regular price $ 157.95

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Tribioscience Herbimycin A, HSP90 Inhibitor; Src Inhibitor (TBI2567)

Research Use Only. Not intended for human use.

Buy Tribioscience products from MSE Supplies at the best value. 

Product Details

Formal Name: (15R)-17-Demethoxy-15 methoxy-11-O-methyl-geldanamycin

Molecular Formula: C30H42N2O9

Formula Weight: 574.68

CAS Number: 70563-58-5

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 6 mg/ml).

Storage: -20°C

Stability: ≥ 2 years.

Applications

HSP90 inhibitor; Src inhibitor

Functions

Ansamycin antibiotic. Inhibits HSP90 and associated client proteins including v-Src, Bcr-Abl, Raf-1 and ErbB2. Reverts tyrosine kinase-induced oncogenic transformation without direct inhibition of phosphorylation activity. Inhibits angiogenesis in a rat retinopathy model.

Application Procedures

First dissolved in DMSO (up to 6 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.

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