Tribioscience DBeQ, p97 AAA ATPase Inhibitor (TBI1196)
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Tribioscience DBeQ, p97 AAA ATPase Inhibitor (TBI1196)
Research Use Only. Not intended for human use.
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Product Details
Formal Name: N,N’-Dibenzylquinazoline-2,4-diamine
Molecular Formula: C22H20N4
Formula Weight: 340.43
CAS Number: 177355-84-9
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
p97 AAA ATPase inhibitor
Functions
A potent, selective and reversible inhibitor of the AAA-ATPase p97 (ATPase associated with diverse cellular activities). Ki=3.2 µM. It blocks ubiquitin-dependent protein clearance pathways. Cell permeable.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.