Histone H3 Monoclonal Antibody Store at -20°C
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Histone H3 Monoclonal Antibody Store at -20°C
| SKU # | E-AB-22003 |
| Reactivity | Human, Mouse, Rat, Yeast |
| Host | Mouse |
| Applications | WB, IF |
Product Details
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat, Yeast |
| Applications | WB, IF |
| Clonality | Monoclonal |
| Immunogen | Recombinant Protein |
| Abbre | Histone H3 |
| Synonyms | H3FA, H3FB, H3FC, H3FD, H3FF, H3FH, H3FI, H3FJ, H3FK, H3FL, HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, Histone H3.1, Histone H3/, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f |
| Swissprot |
P68431Q71DI3P84243
|
| Calculated MW | 15 kDa |
| Observed MW | 15 kDa
|
| Cellular Localization | Extracellular region or secreted, extracellular exosome, extracellular region, Nucleus, nuclear chromosome, nuclear chromosome, telomeric region, nuclear nucleosome, nucleoplasm, nucleus, Other locations: nucleosome, protein complex. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Clone No. | 5B1 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-300 |
| IF | 1:100-500 |
| IP | 1:100-1:300 |
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.