Product Details
Formal Name: (11a, 13E,15S)-11,15-Dihydroxy-9-oxo-prost-13-en-1-oic acid
Alternate Names: PGE1; Alprostadil
Molecular Formula: C20H34O5
Formula Weight: 354.49
CAS Number: 745-65-3
Purity: >98%
Formulation: Powder
Solubility: Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (15 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Endogenous prostaglandin
Functions
PGE1 is an endogenous prostaglandin with vasodilatory, anti-platelet, and anti-hypertensive activities. It is in clinical use for the treatment of erectile dysfunction and the emergency management of infants with patent ductus arteriosus. It has also been used in the treatment of peripheral arterial occlusive disease (PAD).
Application Procedures
First dissolved in DMSO (up to at least 25 mg/ml) or in Ethanol (15 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.