(Hyaluronate 4-glycanohydrolase; EC 3.2.1.35 ) Hyaluronidase catalyzes the depolymerization of mucopolysaccharides, hyaluronic acid, and the chondroitin sulfates A and C. The enzyme is widely distributed in animal tissues but is found in great concentrations in the bovine and ovine testes. It is also produced by a number of bacteria. Hyaluronidase from bovine testes has a molecular weight of 55,000. Purified hyaluronidase is used clinically for the intradermal administration of large volumes of fluid when intravenous injections are contraindicated. The enzyme is administered prior to or simultaneously with the fluid and it facilitates absorption of the fluid.
Tribioscience Hyaluronidase, Enzyme Activity (TBP0072)
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Tribioscience Hyaluronidase, Enzyme Activity (TBP0072)
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Product Details
Form: Freeze-dried powder
Solubility: Distilled water or dilute buffer
Stability: Store at -20° C (-4° F)
Activity: >300 U/mg
Protein: 90%
Unit Definition
The amount of enzyme which liberates one micromole of N-acetylglucosamine per minute at 37°C and pH 4.0.
Applications