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Description: CD8A is a gene that encodes the CD8 antigen, a cell surface glycoprotein primarily found on cytotoxic T cells (CD8+ T cells). The CD8 antigen acts as a coreceptor with the T-cell receptor (TCR) to recognize antigens presented by class I MHC molecules on antigen-presenting cells. CD8A is a significant prognostic marker in various cancers, including bladder cancer (BCa), hepatocellular carcinoma, metastatic melanoma, and head and neck squamous cell carcinoma.
Applications:
- in vivo CD8+ T cel depletion
- Western blot
Molecular Weight: 150 kDa
Immunogen: Mouse CTL clone L3
Host: Rat
Isotype: Rat IgG2b, kappa
Concentration: 4 mg/ml
Purity: >95%
Formulation: PBS, pH 7.0, No stabilizers or preservatives.
Endotoxin: < 2EU/mg
Clonality: Monoclonal
Sterility: 0.2 µm filtered
Storage: Store at 4°C for one month. Store at -20°C for long-term storage.