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Description: NGF is a neurotrophic protein crucial for the growth, differentiation, and survival of certain neurons. Beyond its developmental roles, NGF significantly influences pain perception by sensitizing nociceptors, thereby increasing responses to noxious stimuli. Elevated NGF levels are associated with hyperalgesia and chronic pain conditions, making it a target for novel analgesic therapies.
Applications:
- in vivo NGF neutralization
- ELISA
Molecular Weight: 150 kDa
Host: Human
Isotype: Human IgG2 kappa
Concentration: 4 mg/ml
Purity: >95%
Formulation: PBS, pH 7.0, no stabilizers or preservatives.
Endotoxin: < 0.5EU/mg
Clonality: Monoclonal
Sterility: 0.2 µm filtered
Storage: 4°C stable for up to one month. Store at -20°C for long-term.