First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
Tribioscience PP1, Src Family Kinase Inhibitor
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Tribioscience PP1, Src Family Kinase Inhibitor
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Product Details
Formal Name: 4-amino-1-tert-butyl-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidine
Molecular Formula: C16H19N5
Formula Weight: 281.63
CAS Number: 172889-26-8
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
Src family kinase inhibitor
Functions
Potent and selective inhibitor of Src family tyrosine kinases. IC50=5 nM (p65lck), IC50=6 nM(P59fynT), IC50=170 nM (p60src). Cell permeable.
Application Procedures