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Tribioscience Etoposide (VP-16), Topoisomerase II Inhibitor

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SKU: TBI1123-100MG
Regular price $ 87.95

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Tribioscience Etoposide (VP-16), Topoisomerase II Inhibitor

Research Use Only. Not intended for human use.

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Product Details

Formal Name: 4′-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-β-D-glucopyranoside

Molecular Formula: C29H32O13

Formula Weight: 588.56

CAS Number: 33419-42-0

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 30 mg/ml).

Storage: RT

Stability: ≥ 2 years.

Applications

Topoisomerase II inhibitor

Functions

Chemotherapeutic agent. Etoposide forms a ternary complex with DNA and topoisomerase II, preventing re-ligation of DNA strands causing DNA cleavage. Blocks the cell cycle in S-phase and G2-phase.

Application Procedures

First dissolved in DMSO (up to 30 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.

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