Product Details
Formal Name: N6,O2′-Dibutyryl adenosine 3′,5′-cyclic monophosphate sodium salt
Alternate Names: Bucladesine Na
Molecular Formula: C18H23N5O8P · Na
Formula Weight: 491.40
CAS Number: 16980-89-5
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (50 mg/ml); water (50 mg/ml)
Storage: -20°C
Stability: ≥ 2 years.
Applications
PKA activator
Functions
Cell-permeable cAMP analog which mimics the effect of endogenous cAMP when applied to cells. Activates PKA. Induces morphological differentiation of astrocytes. Promotes differentiation of dopaminergic neurons from hPSCs (in cocktails with other agents).
Application Procedures
First dissolved in DMSO (50 mg/ml); water (50 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.