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Tribioscience Clozapine, Dopamine D2/D4 Aantagonist (TBI1140)

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SKU: TBI1140-100MG
Regular price $ 87.95

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Tribioscience Clozapine, Dopamine D2/D4 Aantagonist (TBI1140)

Research Use Only. Not intended for human use.

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Product Details

Formal Name: 8-Chloro-11-(4-methyl-1-piperazinyl)-5/H-dibenzo[b,e]diazepine

Molecular Formula: C18H19ClN4

Formula Weight: 326.82

CAS Number: 5786-21-0

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 30 mg/ml).

Storage: RT

Stability: ≥ 1 year.

Applications

Dopamine D2/D4 antagonist

Functions

Dopamine D4 and D2 receptor antagonist. High affinity for the cloned rat dopamine D4 receptor (Ki < 20 nM). Atypical neuroleptic agent. Antagonist at 5HT2A, 5HT2C, 5HT3, 5HT6 and 5HT7 receptors.

Application Procedures

First dissolved in DMSO (up to 30 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.

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