Product Details
Formal Name: (5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol
Molecular Formula: C25H31N5O4
Formula Weight: 465.54
CAS Number: 1009298-09-2
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 30 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
mTOR kinase inhibitor
Functions
AZD8055 is a potent and highly selective inhibitor of mammalian target of rapamycin kinase (mTOR) kinase (IC50 = 0.8 nM). mTOR acts as a nutrient/energy/redox sensor and a controller of protein synthesis – as such it is a very important target for cancer research. It has been investigated as a potential chemotherapeutic for various cancers.
Application Procedures
First dissolved in DMSO (up to 30 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.