Thousands of Quick Ship Products

Bulk Pricing

Customization Solutions

8AM-5PM M-F Customer Service (MTN)

Tribioscience 6-Mercaptopurine, Purine Antimetabolite and Immunomodulator (TBI4698)

SKU: TBI4698-200MG
Regular price $ 44.95

Still have questions? Ask our experts!

Tribioscience 6-Mercaptopurine, Purine Antimetabolite and Immunomodulator (TBI4698)

Buy Tribioscience products from MSE Supplies at the best value. 

Product Details

Formal Name: 3,7-Dihydropurine-6-thione monohydrate

Alternate Names: 6-MP

Molecular Formula: C5H4N4S·H2O

Formula Weight: 170.19

CAS Number: 6112-76-1

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 5 mg/ml with warming)

Storage: RT

Stability: ≥ 2 years.

Applications

Purine antimetabolite and immunomodulator

Functions

Purine antimetabolite drug used to treat acute lymphocytic leukemia, Crohn’s disease, ulcerative colitis, and inflammatory bowel disease. It inhibits DNA synthesis by inhibiting the production of purine containing nucleotides. The immunomodulatory activity of 6-Mercaptopurine is mainly the result of the 6-MP metabolite 6-thioguanine triphosphate (6-TGTP) binding to small GTPase Rac1.

Application Procedures

First dissolved in DMSO (up to 50 mg/ml) or in Ethanol (up to 5 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.