Polysciences Inc. Polydioxanone, IV 2.5 dL/g
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Polysciences Inc. Polydioxanone, IV 2.5 dL/g
Polysciences Inc. Polydioxanone, IV 2.5 dL/g is poly(p-dioxanone), or PDO, CAS Number 31621-87-1, with the linear formula (C4H6O3)n. This highly crystalline polylactone ester comes as a white to off-white solid with a viscosity of about 2.5 dL/g. Researchers study PDO-based biomaterials for drug and gene delivery and for tissue engineering. The polymer is hygroscopic, so protect it from moisture and store it at -20°C. Sizes are 5 g and 25 g.
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Product Overview
Polydioxanone (PDO) is a polylactone ester with high degrees of crystallinity and is known for its use in filament sutures, meshes, clips, and other flexible absorbable devices. PDO is available as colorless or dyed homopolymer or copolymerized with PLA and/or PGA. A systematic review of implantable PDO products has shown high-levels of safety in use. The well-known safety profile of PDO has led to further research on PDO-based bio-materials with modified properties for tissue engineering and drug/gene delivery applications.
Poly-p-dioxanone
poly(p-dioxanone)
Properties
References
1. Martins, Joana A., et al. "Polydioxanone implants: a systematic review on safety and performance in patients." Journal of biomaterials applications 34.7 (2020): 902-916.
http://dx.doi.org/10.1177/0885328219888841
2. Myung, Yujin, and Chinkoo Jung. "Mini-midface lift using polydioxanone cog threads." Plastic and Reconstructive Surgery Global Open 8.6 (2020). doi: 10.1097/GOX.0000000000002920
Safety and Storage
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See the full range in Polysciences Polymer Reagents.