COX-2 Monoclonal Antibody Synonyms COX-2
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COX-2 Monoclonal Antibody Synonyms COX-2
Product Details
| Host | Mouse |
| Reactivity | Human |
| Applications | IHC-P |
| Synonyms | COX-2 |
| Cellular Localization | cell membrane/Cytoplasm |
| Tissue Specificity | Colon cancer |
| Storage | The RTU should be stored at 2~8°C protecting from light (Do not freeze),Valid for 12 months. |
| Shipping | Ice bag |
Background
Cox-2 is an inducible enzyme which can be involved in the cell reactions of growth factors, tumor promoters and cytokines, all of those factors can induce cox-2 overexpression. Cox-2 is also involved in the synthesis of prostaglandins. Cox-2 expression is significantly increased in 85-90% in colorectal adenocarcinoma patients, while cox-1 expression is unchanged.