PIKFYVE Polyclonal Antibody Store at -20°C
Couldn't load pickup availability
Still have questions? Ask our experts!
PIKFYVE Polyclonal Antibody Store at -20°C
| SKU # | E-AB-10902 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human PIKFYV |
| Abbre | PIKFYV |
| Synonyms | 1 phosphatidylinositol 3 phosphate 5 kinase, 1 phosphatidylinositol 4 phosphate 5 kinase, 1-phosphatidylinositol 3-phosphate 5-kinase, CFD, FAB1, FY, FYV1, FYVE finger containing phosphoinositide kinase, S. cerevisiae, epididymis luminal protein 37, homolog of |
| Swissprot | |
| Cellular Localization | Endosome membrane. Mainly associated with membranes of the late endocytic pathway. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol ring. This gene encodes an enzyme (PIKfyve; also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3,5)biphosphate.