NCOR1 Polyclonal Antibody Store at -20°C
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NCOR1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-12591 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human NCOR1 |
| Abbre | NCOR1 |
| Synonyms | KIAA1047, N CoR, N CoR1, N Cor/SMRT corepressor Rip13, N-CoR, N-CoR1, NCOR 1, NCOR1, NCoR, Ncor1, Nuclear receptor co repressor 1, Nuclear receptor corepressor 1, RIP13, Retinoid X receptor interacting protein 13, Rxrip13, hN CoR, hNCoR, thyroid hormone and retinoic acid |
| Swissprot | |
| Cellular Localization | Nucleus. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:100-1:300 |
Background
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.