IKBKE Polyclonal Antibody Store at -20°C
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IKBKE Polyclonal Antibody Store at -20°C
| SKU # | E-AB-15127 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human IKBKE |
| Abbre | IKBKE |
| Synonyms | I kappa B kinase epsilon, I-kappa-B kinase epsilon, IKK related kinase epsilon, IKK-E, IKK-epsilon, IKK-i, IKKE, IKKI, IKKepsilon, IkBKE, Inducible I kappa B kinase, Inducible I kappa-B kinase, Inducible IkappaB kinase, Inhibitor of kappa light polypeptide gene e |
| Swissprot | |
| Cellular Localization | Cytoplasm. Nucleus. Nucleus>PML body. Targeting to PML nuclear bodies upon DNA damage is TOPORS-dependent. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines