SLC12A5 Polyclonal Antibody Reactivity Rat
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SLC12A5 Polyclonal Antibody Reactivity Rat
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| SKU # | E-AB-52074 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
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Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human SLC12A5 |
| Abbre | SLC12A5 |
| Synonyms | Electroneutral potassium chloride cotransporter 2,  Electroneutral potassium-chloride cotransporter 2,  Erythroid K Cl cotransporter 2,  Furosemide sensitive K Cl cotransporter,  K-Cl cotransporter 2,  KCC 2,  KCC2,  KIAA1176,  Neuronal ,  Neuronal K Cl cotransporter,  hKCC2 |
| Swissprot | |
| Cellular Localization | Membrane. |
| Concentration | 1.44 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:40-1:200 |
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Background
K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms.