PROC Polyclonal Antibody
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PROC Polyclonal Antibody
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| SKU # | E-AB-19808 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
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Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human PROC |
| Abbre | PROC |
| Synonyms | APC,  Activation peptide,  Anticoagulant protein C,  Autoprothrombin IIA,  Blood coagulation factor XIV,  EC 3.4.21.69,  PC,  PROC,  PROC1,  Protein C (inactivator of coagulation factors Va and VIIIa),  THPH3,  THPH4,  Vitamin K dependent protein C,  proC |
| Swissprot | |
| Cellular Localization | Secreted. Golgi apparatus. Endoplasmic reticulum. |
| Concentration | 3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cardiovascular |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:100-1:300 |
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Background Â
This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009]