GCKR Polyclonal Antibody Host Rabbit
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GCKR Polyclonal Antibody Host Rabbit
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| SKU # | E-AB-13267 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
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Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human GCKR |
| Abbre | GCKR |
| Synonyms | FGQTL5,  GCK,  GCKR,  GKRP,  GLRE,  Glucokinase,  Glucokinase regulator,  Glucokinase regulatory protein,  HK IV,  HK4,  Hexokinase 4 regulator,  Hexokinase type IV,  Hexokinase-4,  Hexokinase-D,  OTTHUMP00000158533,  glucokinase (hexokinase 4) regulator |
| Swissprot | |
| Calculated MW | 69 kDa |
| Cellular Localization | Cytosol, Nucleus, nucleoplasm, Other locations: cytoplasm. |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer,  Cardiovascular,  Metabolism,  Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
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Background
This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).