GALR1 Polyclonal Antibody
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GALR1 Polyclonal Antibody
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| SKU # | E-AB-19892 |
| Reactivity | Human,  Mouse,  Rat |
| Host | Rabbit |
| Applications | IHC |
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Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human,  Mouse,  Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human GALR1 |
| Abbre | GALR1 |
| Synonyms | brain,  GAL1R,  GALNR,  GALNR1,  GALR1,  Galanin receptor,  Galanin receptor type 1,  gal receptor 1,  gal-1 receptor,  galanin receptor 1,  galanin-1 receptor,  hugal 1-r |
| Swissprot | |
| Cellular Localization | Cell membrane, Multi-pass membrane protein. |
| Concentration | 1.8 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cardiovascular,  Neuroscience,  Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
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Background Â
The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.