ERAS Polyclonal Antibody
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ERAS Polyclonal Antibody
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| SKU # | E-AB-13219 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
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Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ERAS |
| Abbre | ERAS |
| Synonyms | E ras,  E-Ras,  ES cell expressed Ras,  Embryonic stem cell expressed Ras,  Embryonic stem cell-expressed Ras,  Eras,  GTPase ERas,  HRAS2,  HRASP,  Ha-Ras2,  MGC126691,  MGC126693,  OTTHUMP00000065857,  RASE,  Small GTPase protein E Ras,  ecat5,  v Ha ras Harvey rat sarcoma viral oncog |
| Swissprot | |
| Calculated MW | 25 kDa |
| Cellular Localization | Cell membrane. |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer,  Epigenetics and Nuclear Signaling,  Developmental Biology,  Signal Transduction,  Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
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Background
This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance.