Ephrin A5 Polyclonal Antibody
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Ephrin A5 Polyclonal Antibody
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| SKU # | E-AB-16408 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
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Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human EFNA5 |
| Abbre | Ephrin A5 |
| Synonyms | AF1,  AL 1,  AL-1,  EFL5,  EFNA5,  EPH-related receptor tyrosine kinase ligand 7,  EPLG7,  Efna5,  Ephrin A5,  Ephrin-A5,  GLC1M,  LERK-7,  LERK7,  RAGS |
| Swissprot | |
| Cellular Localization | Cell membrane. Membrane>caveola. Compartmentalized in discrete caveolae-like membrane microdomains. |
| Concentration | 0.8 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
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Background
Ephrin-A5, a member of the ephrin gene family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997).