CAPN3 Polyclonal Antibody Reactivity Mouse
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CAPN3 Polyclonal Antibody Reactivity Mouse
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| SKU # | E-AB-52137 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
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Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human CAPN3 |
| Abbre | CAPN3 |
| Synonyms | (p94),  large [catalytic] subunit,  large polypeptide L3,  CAN3,  CANP 3,  CANP3,  CANPL3,  CAPN3,  Calcium-activated neutral proteinase 3,  Calpain L3,  Calpain large polypeptide L3 ,  Calpain p94,  Calpain-3,  LGMD 2A,  LGMD2,  LGMD2A,  Lp82,  Lp85,  MGC10,  calpain,  calpain 3,  calpain p94 |
| Swissprot | |
| Cellular Localization | Cytoplasm. |
| Concentration | 1.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cell Biology,  Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:30-1:150 |
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Background
Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.