S100A12 Polyclonal Antibody Host Rabbit
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S100A12 Polyclonal Antibody Host Rabbit
| SKU # | E-AB-40442 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant Human Protein S100-A12 protein |
| Abbre | S100A12 |
| Synonyms | CAGC, CGRP, Calcitermin, Calcium-binding protein in amniotic fluid 1, Calgranulin C, ENRAGE, Extracellular newly identified RAGE-binding protein, MRP6, Neutrophil S100 protein, Protein S100 A12, S1, migration inhibitory factor-related protein 6, p6, CAAF1 |
| Swissprot | |
| Cellular Localization | Cell membrane, Cytoplasm, Cytoskeleton, Membrane, Secreted. |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Immunology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities.