Phospho-PKC Delta (Thr507) Polyclonal Antibody
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Phospho-PKC Delta (Thr507) Polyclonal Antibody
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| SKU # | E-AB-20968 |
| Reactivity | Human,  Mouse,  Rat |
| Host | Rabbit |
| Applications | WB,  IHC-p |
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Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human,  Mouse,  Rat |
| Applications | WB,  IHC-p |
| Clonality | Polyclonal |
| Immunogen | Synthesized peptide derived from human PKC δ around the phosphorylation site of Thr507 |
| Synonyms | CVID9,  D14Ertd420e,  KPCD,  Kinase PKC delta,  MAY 1,  MAY1,  MGC49908,  PCKd,  PKC d,  PKC delta,  PKCD,  PKCdelta,  PRKC D,  PRKC delta,  Prkcd,  Protein Kinase C delta,  Protein Kinase Cdelta,  Protein kinase C delta VIII,  Protein kinase C delta type,  Tyrosine,  nPKC delta,  nPKC-delta |
| Swissprot | |
| Calculated MW | 77 kDa |
| Observed MW | 78 kDa |
| Cellular Localization | Cytoplasm. Membrane. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer,  Neuroscience,  Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
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Background Â
This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.