Phospho-MAP3K5 (Ser966) Polyclonal Antibody
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Phospho-MAP3K5 (Ser966) Polyclonal Antibody
| SKU # | E-AB-20813 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC-p |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC-p |
| Clonality | Polyclonal |
| Immunogen | Synthesized peptide derived from human ASK 1 around the phosphorylation site of Ser966 |
| Synonyms | ASK 1, ASK-1, ASK1, Apoptosis signal regulating kinase 1, Apoptosis signal-regulating kinase 1, M3K5, MAP/ERK kinase kinase 5, MAP3K5, MAPK/ERK kinase kinase 5, MAPKKK5, MEK kinase 5, MEKK 5, MEKK5, Mitogen activated protein kinase kinase kinase 5, Mitogen-activat |
| Swissprot | |
| Calculated MW | 155 kDa |
| Observed MW | 155 kDa
|
| Cellular Localization | Cytosol, Endoplasmic reticulum, IRE1-TRAF2-ASK1 complex, Plasma Membrane, external side of plasma membrane, Other locations: protein complex, protein kinase complex. |
| Tissue Specificity | Abundantly expressed in heart and pancreas |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Cardiovascular |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
Background
Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.