Phospho-JAK1 (Tyr1022) Polyclonal Antibody
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Phospho-JAK1 (Tyr1022) Polyclonal Antibody
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| SKU # | E-AB-20913 |
| Reactivity | Human,  Mouse,  Rat |
| Host | Rabbit |
| Applications | WB,  IHC-p,  IF |
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Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human,  Mouse,  Rat |
| Applications | WB,  IHC-p,  IF |
| Clonality | Polyclonal |
| Immunogen | Synthesized peptide derived from human JAK1 around the phosphorylation site of Tyr1022 |
| Abbre | JAK1 (phospho Tyr1022) |
| Synonyms | JAK 1,  JAK 1A,  JAK 1B,  JAK-1,  JAK1,  JAK1A,  JAK1B,  JTK3,  Janus kinase 1,  Janus kinase 1 (a protein tyrosine kinase),  Tyrosine protein kinase JAK 1,  Tyrosine protein kinase JAK1,  Tyrosine-protein kinase JAK1 |
| Swissprot | |
| Calculated MW | 132 kDa |
| Observed MW | 132 kDa |
| Cellular Localization | Endomembrane system. Wholly intracellular, possibly membrane associated. |
| Tissue Specificity | Expressed at higher levels in primary colon tumors than in normal colon tissue. The expression level in metastatic colon tumors is comparable to the expression level in normal colon tissue. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer,  Cell Biology,  Epigenetics and Nuclear Signaling,  Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
| IF | 1:50-1:200 |
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Background Â
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.