Phospho-FOXO3 (Ser253) Polyclonal Antibody
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Phospho-FOXO3 (Ser253) Polyclonal Antibody
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| SKU # | E-AB-20878 |
| Reactivity | Human,  Mouse,  Rat |
| Host | Rabbit |
| Applications | WB,  IHC-p,  IF |
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Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human,  Mouse,  Rat |
| Applications | WB,  IHC-p,  IF |
| Clonality | Polyclonal |
| Immunogen | Synthesized peptide derived from human FoxO3A around the phosphorylation site of Ser253 |
| Synonyms | AF6q21,  AF6q21 protein,  DKFZp781A0677,  FKHR2,  FKHRL 1,  FKHRL1,  FKHRL1P2,  Forkhead (Drosophila) homolog (rhabdomyosarcoma) like 1,  Forkhead Drosophila homolog of in rhabdomyosarcoma ,  Forkhead box O3,  Forkhead box O3A,  Forkhead box protein O3,  Forkhead box protein O3A |
| Swissprot | |
| Calculated MW | 71 kDa |
| Observed MW | 97 kDa |
| Cellular Localization | Cytoplasm>cytosol. Nucleus. Translocates to the nucleus upon oxidative stress and in the absence of survival factors. |
| Tissue Specificity | Ubiquitous |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer,  Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
| IF | 1:200-1:1000 |
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Background Â
Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'.