NDUFA1 Polyclonal Antibody
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NDUFA1 Polyclonal Antibody
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| SKU # | E-AB-11424 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
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Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human NDUFA1 |
| Abbre | NDUFA1 |
| Synonyms | B. taurus,  CI MWFE,  CI-MWFE,  Complex I MWFE,  Complex I-MWFE,  MWFE,  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1,  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1 7.5kDa,  NADH dehydrogenase [ubiquinone] 1 alpha su,  complex I MWFE subunit,  homolog of |
| Swissprot | |
| Cellular Localization | Mitochondrion inner membrane. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer,  Metabolism,  Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| IHCÂ | 1:50-1:200 |
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Background
The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone.It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I.The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane.