COL3A1 Monoclonal Antibody
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COL3A1 Monoclonal Antibody
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| SKU # | E-AB-22071 |
| Reactivity | Human,  Mouse,  Rat |
| Host | Mouse |
| Applications | WB,  IHC-p,  IF |
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Product Details
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Human,  Mouse,  Rat |
| Applications | WB,  IHC-p,  IF |
| Clonality | Monoclonal |
| Immunogen | Synthetic Peptide |
| Abbre | Collagen III |
| Synonyms | Alpha 1 type III collagen,  Alpha1 (III) collagen,  CO3A1,  COL 3A1,  COL3A1,  Collagen III alpha 1 chain precursor,  Collagen III alpha 1 polypeptide,  Collagen alpha 1(III) chain,  Collagen alpha-1(III) chain,  Collagen type III alpha 1 (Ehlers Danlos syndrome type IV au |
| Swissprot | |
| Calculated MW | 139 kDa |
| Observed MW | 138 kDa |
| Cellular Localization | Secreted>extracellular space>extracellular matrix. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Research Areas | Cancer,  Signal Transduction,  Stem Cells |
| Clone No. | 5G2 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-300 |
| IF | 1:100-1:300 |
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Background
This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.